Clemson faces a top-35 RPI Virginia Tech team in search of its third ACC road win.
Elijah Thomas posted a double-double with 12 points and 11 rebounds.
Clemson takes to the road to face Miami at the Watsco Center on Saturday.
The Clemson senior graduated in August 2016 and is the Tigers' leading scorer this season.
Marcquise Reed led the Tigers with 21 points, his second such effort against the Deacs this season.
Clemson takes on the Demon Deacons, looking for a regular-season series sweep for the first time since 2011-12.
Clemson was led by Shelton Mitchell's career-high 23-point performance.
Clemson looks for its first win at Cameron Indoor Stadium since 1995.
Orange freshman Tyus Battle hit a three-pointer as time expired.
Tigers are in search of a third straight win over the Orange.
No. 15 Florida State defeated Clemson, 109-61.
Clemson is in search of its second win over a top-25 team on the road this season.